Human Rabies Immune Globulin Vs Vaccine

Human rabies immune globulin (HRIG) is the IgG fraction of plasma from human donors who have received multiple doses of rabies vaccine and have high levels of anti-rabies antibody. HRIG is administered once to previously unvaccinated persons exposed to a rabid animal to provide rabies virus neutralizing antibody coverage until the patient responds to vaccination by actively producing virus-neutralizing antibodies. HRIG is administered once on day 0 at the time postexposure prophylaxis (PEP) is initiated, in conjunction with human rabies vaccine. If HRIG was not administered when vaccination was begun on day 0, it can be administered up to and including day 7 of the PEP series.   Human rabies vaccine is a preparation of rabies fixed virus inoculated into Vero cell. Injection of this vaccine can induce immunity against rabies virus to prevent rabies since rabies is a fatal disease. BioShoot is 0.5ml/vial after reconstitution. The vaccine tilter should…