Why choose PLLA fillers? PLLA stimulates the proliferation of collagen by regenerating fibroblasts. The instant filling effect of PLLA will gradually disappear from 3 to 7 days after injection with the absorption of the solvent.PLLA microparticles will colonize in situ and begin to work.1 month after injection, PLLA microparticles are encapsulated by macrophages and lymphocytes generated by foreign body inflammation. 3 months after injection, PLLA microparticles shrink gradually and are hydrolyzed into PLA or LA. After phagocytosis, the final metabolites are carbon dioxide and water. The reaction will stimulate the proliferation of fibroblasts. Six months after injection, the proliferation rate of fibroblasts reaches climax and begins to secrete collagen vastly, mainly type I collagen, to fill the tissues. It is noteworthy that fibroblasts function as a regulators of collagen proliferation in these reactions. This means when original PLLA microparticles are metabolized, t…
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